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HCMV Vaccine Development Targets Immunomodulatory Proteins

Guest Commentary by Anamaris Colberg-Poley* Human cytomegalovirus (HCMV) can cause severe disease in immunocompromised individuals and in congenitally infected infants, thus the development of an HCMV vaccine has been a national priority over the last few decades.  Despite attempts similar to those which have proven successful for other herpesviruses, such as varicella zoster virus, attenuated HCMV […]

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New and Notable This Week

This week’s selection of recently published papers from MDPI journals.

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Recent Updates to our Manuscript Submission and Publishing Systems

Here a short summary of a few recent changes to our submission and publishing systems.

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Towards Therapeutic Use of Antimicrobial Peptides: Conferring Cell Selectivity by Introducing Specificity Determinants

Guest Commentary by Guangshun Wang* We are living in an era of antibiotic resistance; fortunately, there is widespread recognition of the consequences of this dilemma. While scientists have long been fascinated by the impressive diversity of antimicrobial peptides (also called host defense peptides) that exist in bacteria, protozoa, fungi, plants, and animals, there is a […]

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Non-coding RNAs: Regulatory Guardians of the Genome

Guest Post by Franck Vazquez* During the last two decades the Central Dogma of Biology, which states that genetic information flows from DNA into messenger RNAs (mRNAs) via transcription, and from mRNAs into functional proteins via translation, has been shown to be far more complicated than what had long been accepted. Indeed, cells transcribe thousands of RNAs, which neither […]

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Kudos to our Peer-Reviewers and Journal Rejection Rates in 2013

Our journals received nearly 20’000 manuscript submissions in 2013, or about 75 submissions per business day. It is a logistical challenge to handle this number of incoming manuscripts, to screen them appropriately, expedite them to external peer-review and to communicate with authors to keep them informed and advise them on revisions. More than 100 in-house […]

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And as such, my first first-author paper (a review) is published! Functional Characteristics and Regulated Expression of Alternatively Spliced Tissue Factor: An Update This review is part of a special issue on tissue factor in malignancy.