Monoclonal Antibody to HCMV Glycoprotein B Blocks Viral Entry and Growth in Trophoblast Progenitor Cells
Guest Commentary by Anamaris Colberg-Poley* Human cytomegalovirus (HCMV) is the major cause of congenital birth infections in developed countries. HCMV can cause severe birth defects including microcephaly, mental retardation, sensorineural hearing loss, and intrauterine growth restriction. However, because of the potential for teratogenicity and toxic effects, no therapeutic treatment is currently approved by the Food […]
More InfoControlling Sugar Intake: A Platform to Predict Glycosylation for Therapeutic Antibodies
Glycoproteins are formed through protein glycosylation, the post-translational addition and processing of covalently bound oligosaccharide chains. Variations in the glycoform of proteins result from multiple factors in this process, such as enzyme and substrate availability, and these differences can influence the stability and biological function of the protein1.
More InfoOpen Access Publishing – Transparency and Accountability in Scientific Research and Publishing
Scientific publishing, and communication in general, has changed rapidly and radically over the past 20 years. With the advent of the Internet, communication and publishing has become affordable to all, to the point that one only needs a few megabytes of online space, a HTML editor and a word processor to claim to be a […]
More InfoFlotillins: Signals from a Raft
Flotillins are highly homologous proteins (known as flotillin-1 and flotillin-2, or reggie-2 and reggie-1, respectively) that localize to membrane rafts (specific cholesterol-rich microdomains in cellular membranes), and are associated with various signaling pathways, cell adhesion, membrane trafficking and axonal growth.
More InfoLeon Terstappen on Circulating Tumor Cells: Biology and Technology
Tumor metastases cause ninety percent of cancer deaths, and occur when cells detach from a primary tumor and form new malignancies elsewhere. This process involves circulating tumor cells (CTC) which intravasate and extravasate (enter and exit the blood vessels) allowing migration to other parts of the body.
More InfoEvolution and Diversification of Snake Venom Toxins
Snake venom toxins are well-known for their profound physiological effects that enable their use as tools to aid basic research and clarify pathological processes; they also have enormous potential in drug design and development. Further, an area of growing interest is the molecular evolution and diversification of these toxins, a particularly rapid and dynamic process for which the underlying mechanisms […]
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成人T細胞白血病は、有効な治療法無く、血液がんなので治療効果もわかりやすい。社会的ニーズも大きい。ANKがん免疫療法のデータを取るには最適と思われる。長期生存例を積み重ね、論文を発表している。 mdpi.com/2571-841X/1/2/…
New #openaccess paper in #Atmosphere "Evaluation of Limiting Sensitivity of the One-Color Laser Fragmentation/Laser-Induced Fluorescence Method in Detection of Nitrobenzene and Nitrotoluene Vapors in the Atmosphere" by Sergei Bobrovnikov et al. 😃mdpi.com/2073-4433/10/1… pic.twitter.com/M9prkjaOgm
#Special_Issue "Oxidative Potential of Atmospheric Aerosols" in #Atmosphere has published FIVE papers! 🎉🎉Read them for free! mdpi.com/journal/atmosp…
Our special issue devoted to SiC miniaturized devices has already published 8 papers. Submit your manuscript by December 31 #siliconcarbide #mems #micromachines #electronicdevices @MDPIOpenAccess @micromach_mdpi mdpi.com/journal/microm…
Traumatic brain injury, clean air and obesity! New research from some of our researchers here at SPGH - Jane Hayworth, @GinaAmbrosini & Jesse Young (@jtyoung_edu) mdpi.com/2072-6643/11/1… mdpi.com/2073-4433/10/1… thelancet.com/journals/lanpu…
New publication: 'Fabrication and In Vitro Characterization of Electrochemically Compacted Collagen/Sulfated Xylorhamnoglycuronan Matrix for Wound Healing Applications' mdpi.com/280232 @GordonGWallace @KangLingzhi @Zhi05845090 @UOW @uowresearch @StVincentsMelb @unimelb pic.twitter.com/cgplK89QvB
What do you think? If mining were done in our open oceans instead of on land or in addition to on land would that benefit the environment? "The analysis presented here shows that, for most elements, extraction from seawater is so…lnkd.in/gaxpwAa lnkd.in/g3bKkDD
NEW RAINE STUDY RESEARCH: Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study mdpi.com/2072-6643/11/1… #rainestudy #oneofuscouldchangeyourlife
Our latest two papers on #alcoholhangover 1. advantages and disadvantages of naturalistic studies. 2. evidence of reverse tolerance to hangover (now with correct links!) @DrSarahBenson @alcoholHRG @SwinCHP mdpi.com/538890 @MDPIOpenAccess mdpi.com/590282
Nanoparticle Delivery Systems in the Treatment of Diabetes Complications mdpi.com/1420-3049/24/2…
Such a pleasure working with @gmasselink @PlymUniResearch on this #coastal #resilience piece for @Water_MDPI (mdpi.com/2073-4441/11/1…). Gerd said, "I wrote a report for @EnvAgency @EAGeomorphology – want to turn it into a paper?" Umm – yes, please. @NERCscience @BLUEcoastUK
Interested in the verification of cybersecurity policies using software product lines?, check out our paper CyberSPL. It is an extension of our paper for the spanish national securtiy conference mdpi.com/2076-3417/9/24… @Applsci @Idea_Group_US @MayteGoLo
📖 Investigating the In Vitro Regeneration Potential of Commercial Cultivars of Brassica @MDPIOpenAccess @sparrow_penny mdpi.com/2223-7747/8/12… pic.twitter.com/RaYtSlcOAP
Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents #miRNA #Biomarkers #Obesity mdpi.com/2072-6643/11/1…
The Interplay between the Endocannabinoid System, #Epilepsy and #Cannabinoids mdpi.com/1422-0067/20/2…
Social Sciences has a special issue on the personal experiences of researchers edited by Dr Pooja Sawrikar @Griffith_Uni : Personal Essays in Social Science. See here - mdpi.com/journal/socsci…
A review on the #endocannabinoid system, #epilepsy and #cannabinoids, with focus on the role of neuro-#inflammation mdpi.com/1422-0067/20/2…