Insights Into MDPI Top Picks: April 2026

This month, we see a range of exciting research published across MDPI’s Open Access journals. Ranging from forensic science techniques, to exploring socioeconomic disadvantage amongst the youth, this article covers a variety of fascinating research, where we also hear from authors of the study and prominent researchers within the field.


Retrieving Seasonal Disaster Records from Early-19th-Century Diaries

Published in Data, April 2026 | Japan Agency for Marine-Earth Science and Technology

Records of global climate events and disasters prior to modern satellite monitoring is largely dependent on historical diaries. However, personal written records are often accompanied with major inconsistencies and are not always reliable sources of information.

Natural disasters, such as fires and floods, are usually triggered by specific variations and patterns in climate. Researchers extracted 19th century records of fire and flood events over 30 years written by Kaneko Kakuson, a Confucian Japanese scholar.

Analysing historical data from Japanese diary entries could help predict seasonal patterns and disaster probabilities in Japan over specific time periods.

The study published in Data sought to analyse historical records for variations in seasonal patterns associated with disaster occurrence in Japan. Furthermore, they wanted to test the limitations and uncertainties associated with reconstructing seasonal trends solely from written records.

The study demonstrates the generation of historical dark data, providing information on fire and flood events which have said to have occurred between 1803 and 1838 in Japan.

Specifically, the records showed that fires were more likely to have occurred between March and June, while floods were more likely to have occurred between June and September due to variations in trends in weather patterns over the span of 30 years.

The authors conclude that these patterns mirror current seasonal probabilities and climate-driven disaster cycles. Dr. Shin Nagai, author of the study and Senior Researcher at the Japan Agency for Marine-Earth Science and Technology, states:

“We believe our published paper will contribute to a deep understanding of the interaction between people and the ecosystem (across) millennia.”

Research on the reliability of historical records provides insights into historical events, including key climate-related information and associated disasters occurring during this time. Additionally, it can help shape a more holistic understanding of long-term climate trends and shifts.


Survey of Cellular Autofluorescence Variation in Saliva Deposits: Implications for Estimating Time Since Deposition

Published in Forensic Sciences, March 2026 | Virginia Commonwealth University, USA

Time-since-deposition is a term and process used in forensic science to determine when biological substances, such as blood or saliva, were left at a crime scene.

Research published in the Open Access journal Forensic Sciences analysed the epithelial cells present within saliva from 50 participants to investigate how they changed over nine months. Using imaging flow cytometry, the researchers generated autofluorescence profiles across nine detector channels to detect and capture spatial information of the cells.

Autofluorescence of epithelial cells (https://doi.org/10.3390/forensicsci6020036)

The above figure captures the clear increase in the autofluorescence intensity of the cells over time. It displays the autofluorescence of epithelial cells from one participant using autofluorescence imaging cytometry across nine channels. The top panel images were taken at day 1 and compared to the bottom two panel images taken at day 280.

Across the board, imaging results show prominent differences in the autofluorescence intensity of the cells over time, meaning that autofluorescence signatures were identified to establish distinct time-since-deposition parameters. The fluorescence intensity of the images increased over time, as illustrated in the comparison panels above.

The authors reassert that, although this technique may not determine time-since-deposition with a high degree of accuracy, it can support the establishment of important temporal signatures. The technique could be instrumental as a preliminary screening protocol in identifying the samples relevant to the crime being investigated.


Diet-Associated Gut Bacterial Microbiota and Metabolome Signatures Linked to Fermented Food Intake in Healthy Postmenopausal Women

Published in Foods, April 2026 | Chulalongkorn University, Thailand & Université Paris-Saclay, France

Research on the microbiome and its impact on health has gained tremendous momentum in the field of health sciences as well as the wellness industry.

However, like many other aspects of health research, the impact of the microbiome in post-menopausal women remains largely unexplored and misunderstood. New research published in Foods addresses this gap, with the study exploring how diet can shape the microbiome in women above 55 years old.

The researchers analysed the gut microbiota and faecal metabolomes of 32 postmenopausal Thai women, with 16 practising vegetarian and 16 omnivorous diets.

Prof. Cheunjit Prakitchaiwattana, associate professor of Food Technology at the Chulonkorn University, discusses the main findings of the study and its relevance in the field:

“[The research shows] how everyday dietary choices shape the gut microbiota and metabolome in postmenopausal women (>55), revealing clear distinctions between omnivorous and vegetarian patterns.

This study highlights the significant role of fermented foods, not only as sources of probiotics, but also as providers of bioactive metabolites and microbes that actively influence gut function.

These findings offer new insight into how plant-based diets and fermented foods can contribute to improved gut health and support healthy aging.”

Understanding the metabolic processes and unique biology of individuals within certain cohorts can help further our understanding of how disease affects specific groups, such as post-menopausal women.

This assists in broadening our understanding of disease and helping to provide more personalised health advice, including advice on food and diet, for those that are at higher risk of developing conditions due to their age, race or gender.


Accessing Optimism: Rethinking Wellbeing, Inclusion, and Belonging for Young People in Britain Who Are Not in Education, Employment, or Training (NEET)

Published in Youth, April 2026 | University of Bath, UK

Youth unemployment is a widespread issue within the UK, with 975,000 of 16–24year olds categorised as not in employment, education or training (NEET) as of March 2026. The perception of these individuals as lacking aspiration or ambition is shaped by certain political narratives.

However, young people lacking participation in education or work is indicative of dire systemic issues present in the UK, relating to deep-rooted class divide and socioeconomic disadvantage.

Shifting the narrative of young people out of employment or education provides policy makers and society with a deeper understanding of their ongoing struggle against systemic issues. Hopeful optimism as opposed to aspiration could help to encourage inclusion of these often marginalised members of the community.

This encapsulates generational disparities ranging from gaps in healthcare and medicine to disadvantages in education and career opportunity. As a result, individuals categorised as NEET have restricted social mobility and are pushed further into the margins of society.

In a study published in Youth, researchers from the University of Bath present a theoretical model of increasing access to hope and optimism, rather than aspiration, to rethink and potentially dismantle the current perspective of NEET individuals.

We hear from Dr. Chris Cunnigham, author of the study and research assistant at the University of Bath, who discusses the aim of the study:

“Young people’s personal experiences are shaped by social processes. In this paper, we unpack the ways in which education becomes positioned as a competitive process by political narratives. We reimagine these narratives to re-orientate the debate away from aspiration and towards ‘Hopeful Optimism’ to present a vision that is centred around inclusion as opposed to exclusion.”

Additionally, Prof. Ceri Brown, author of the study and Professor of Childhood, Inclusion and Education Policy, addresses important points on how fostering optimism can encourage inclusion amongst young people.

“We position optimism not as a personal trait, but as a socially and structurally produced resource, grounded in young people’s experiences of recognition, inclusion, and belonging. As a collective and present-oriented construct, optimism highlights that engagement depends on whether young people feel valued, connected, and able to imagine viable futures.

Expanding access to optimism, therefore, offers a critical pathway for strengthening belonging, wellbeing, and sustained participation.”

The authors hope that the proposed framework of instilling hopeful optimism could be used amongst policy makers to shift the current political narrative and foster a deeper understanding of the struggles NEET individuals face throughout their lives.


Click here to access the full list of MDPI Journals where you can discover the latest science, ranging from research in education policy and climate research, to forensic science and more.