The Proteasome Activator PA28γ and P53: It Takes Two to Tango, but Which One Takes the Lead?

The phosphoprotein p53 was trivially named after the apparent molecular mass it runs on SDS-PAGE, i.e., 53-kilodalton (kDa). Ever since its discovery in 1979 by several groups simultaneously, this extraordinary protein has captured the imagination of life scientists. p53 is likely the most extensively studied protein in cell biological research. To underscore its importance, p53 […]

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Conference Exhibitions and Sponsorships in 2014

MDPI journals and staff will be present and/or sponsor several academic events in 2014. Here is a current selection (we will update this list from time to time to include more). If you are organizing a conference related to a topic covered by one of our journals, please suggest your event for our consideration at […]

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New and Notable This Week

This week’s selection of recently published papers from MDPI journals.

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New and Notable This Week

This week’s selection of recently published papers from MDPI journals.

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HCMV Vaccine Development Targets Immunomodulatory Proteins

Guest Commentary by Anamaris Colberg-Poley* Human cytomegalovirus (HCMV) can cause severe disease in immunocompromised individuals and in congenitally infected infants, thus the development of an HCMV vaccine has been a national priority over the last few decades.  Despite attempts similar to those which have proven successful for other herpesviruses, such as varicella zoster virus, attenuated HCMV […]

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New and Notable This Week

This week’s selection of recently published papers from MDPI journals.

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Recent Updates to our Manuscript Submission and Publishing Systems

Here a short summary of a few recent changes to our submission and publishing systems.

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Towards Therapeutic Use of Antimicrobial Peptides: Conferring Cell Selectivity by Introducing Specificity Determinants

Guest Commentary by Guangshun Wang* We are living in an era of antibiotic resistance; fortunately, there is widespread recognition of the consequences of this dilemma. While scientists have long been fascinated by the impressive diversity of antimicrobial peptides (also called host defense peptides) that exist in bacteria, protozoa, fungi, plants, and animals, there is a […]

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Non-coding RNAs: Regulatory Guardians of the Genome

Guest Post by Franck Vazquez* During the last two decades the Central Dogma of Biology, which states that genetic information flows from DNA into messenger RNAs (mRNAs) via transcription, and from mRNAs into functional proteins via translation, has been shown to be far more complicated than what had long been accepted. Indeed, cells transcribe thousands of RNAs, which neither […]

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