Flotillins: Signals from a Raft

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Flotillins are highly homologous proteins (known as flotillin-1 and flotillin-2, or reggie-2 and reggie-1, respectively) that localize to membrane rafts (specific cholesterol-rich microdomains in cellular membranes), and are associated with various signaling pathways, cell adhesion, membrane trafficking and axonal growth.

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